CASE REPORT

OFTALMOLOGI : Jurnal Kesehatan Mata Indonesia, 30 Dec 2020 | 1
Year : 2020 | Volume: 2 | Issue: 2 | Pages : 1

BENZATHINE PENICILLIN G INTRAMUSCULAR SUCCESSFUL
TREATMENT OF OCULAR SYPHILIS WITH HUMAN
IMMUNODEFICIENCY VIRUS POSITIVE : A CASE REPORT

  • 1Department of Ophthalmology,Faculty of Medicine,Hasanuddin University,Makassar,Indonesia, , ID
  • 2Department of Ophthalmology,Faculty of Medicine,Hasanuddin University,Makassar,Indonesia, , ID
  • 3Department of Ophthalmology,Faculty of Medicine,Hasanuddin University,Makassar,Indonesia, , ID
  • 42Department of Dermatovenerology,Faculty of Medicine,Hasanuddin University,Makassar,Indonesia, , ID

Introduction: Ocular Syphilis is a manifestation of multisystemic chronic infection caused by the
spirochete Treponema pallidum, it can affect all structures and may present as anterior uveitis, posterior
uveitis, panuveitis, retinitis, papillitis, making it “a great masquerader”.
Objective : To report successful treatment of ocular syphilis co infection with human immunodeficiency
virus positive with Benzathine Penicillin G intramuscular.
Case Presentation : A 28 year old man (heterosexual) presented with painless blurring of his eyes of
three month’s duration. His visual acuity was hand movement in his right eye and 1/60 in the left with no
dermatology lesion, funduscopy finding papillitis and vitreous cells in both eyes with retinal vasculitis and
intraretinal hemorrhage in inferior region in left eye, serological tests revealed VDRL and TPHA test
positive with ELISA was positive for human immunodeficiency virus. The patient immediately treated with
benzathine penicillin G 2.4 million units intramuscularly once weekly for three consecutive weeks and
antiretroviral. After three weeks, his visual acuity showed improvement and decreased VDRL titer three
months later.
Conclusion: Ocular Syphilis with HIV positive is curable with Penicillin G Intramuscular, with early
detection and treatment are important for a good visual outcome.

Keywords: benzathine, ocular, penicillin, syphilis

Citation: Marco Angelo Liwan*,Sitti Soraya Taufik,Hasnah B Eka,Safrudin Amin,Marco Angelo Liwan,Sitti Soraya Taufik,Hasnah B Eka,Safrudin Amin ( 2020), BENZATHINE PENICILLIN G INTRAMUSCULAR SUCCESSFUL
TREATMENT OF OCULAR SYPHILIS WITH HUMAN
IMMUNODEFICIENCY VIRUS POSITIVE : A CASE REPORT. OFTALMOLOGI : Jurnal Kesehatan Mata Indonesia, 2(2): 1

Received: 26/12/2020; Accepted: 26/12/2020;
Published: 30/12/2020

Edited by:

Marco Angelo Liwan, Department of Ophthalmology,Faculty of Medicine,Hasanuddin University,Makassar,Indonesia, , ID

Reviewed by:

Antonia Kartika , , PMN RS Mata Cicendo Bandung, US

Tim Editor , , PMN RS Mata Cicendo Bandung, ID

*Correspondence: Marco Angelo Liwan,